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The club was founded in Fléron as the Fléron Basket Club in 1967. After being an amateur league for its first years, the team hired its first professional coach in 1975. In 1977 and 1981, the Fléron promoted to the first regional league. In 1983, the club made its debut on the national level as it promoted to the Fourth National Division. In 2000, the club decided to merge with BC Hannut and Essor Hannut, relocating to the city of Liège.

After the move to Lìege, the club quickly promoted to the First National League. In 2001, the club's debut in Europe was made after it qualified as 7th in the previous season. In the 2001–02 FIBA Korać Cup, the team lost to French side Racing Paris in the first round. Three years later, in 2004, the team wins its first silverware when it captures the Belgian Basketball Cup for the first time.

In the 2008–09 season, the team had its best European campaign when it reached the Top 16 of the 2008–09 FIBA EuroChallenge. In 2010, Liège played in the championship playoffs for the first time, but loses to Spirou Charleroi.

Since the 2021–22 season, Liège plays in the BNXT League, in which the national leagues of Belgium and the Netherlands have been merged. After the 2020s were characterised mainly by financial problems for Liège, the club was purchased by an American investors group in 2022. The Mickael Sports Group, owned by Ernie Cambo, purchased all shares in the team. Following the acquisition, head coach Lionel Bosco was sacked and replaced by Brad Greenberg.

On October 3, the club announced that they will be boycotting the away-game against Antwerp Giants on October 28 because of "partisan" refereeing in away-games, also saynig that "Belgian players get better calls then foreigners. The BNXT League responded by saying that if they actually pull through, Liège will be refused access to the playoffs on top of a €2500 fine. The League put the deadline for the decision on October 10. On October 9, they announced that the will play against the Antwerp Giants.