Stadium: Panther Stadium at Blackshear Field Round: 1
Home Manager: Eric Dooley Away Manager: Michael Haywood
| NCAA Division I, FCS, Playoffs | 2017/11/26 00:00 | Texas Southern v Prairie View A&M | L | 16-30 |
| NCAAF FCS | 2018/11/18 01:30 | Arkansas-Pine Bluff v Texas Southern | L | 15-10 |
| NCAAF FCS | 2018/11/03 19:00 | Texas Southern v Alabama State | L | 21-30 |
| NCAA Division I, FCS, Playoffs | 2018/10/27 19:00 | Texas Southern v Mississippi Valley | W | 42-14 |
| NCAA Division I, FCS, Playoffs | 2018/10/20 19:00 | Texas Southern v Southern | L | 7-21 |
| NCAA Division I, FCS, Playoffs | 2018/10/13 23:00 | Grambling State v Texas Southern | L | 34-21 |
| NCAA Division I, FCS, Playoffs | 2018/10/06 23:00 | Alabama A&M v Texas Southern | L | 42-21 |
| NCAA Division I, FCS, Playoffs | 2018/09/23 00:00 | Texas Southern v Houston | L | 14-70 |
| NCAA Division I, FCS, Playoffs | 2018/09/15 23:00 | Texas Southern v Alcorn State | L | 15-27 |
| NCAAF FCS | 2018/11/17 19:00 | Alabama State v Prairie View A&M | W | 13-66 |
| NCAAF FCS | 2018/11/03 19:00 | Prairie View A&M v Jackson State | L | 28-34 |
| NCAA Division I, FCS, Playoffs | 2018/10/27 19:00 | Prairie View A&M v Alcorn State | L | 13-27 |
| NCAA Division I, FCS, Playoffs | 2018/10/13 22:00 | Southern v Prairie View A&M | L | 38-0 |
| NCAA Division I, FCS, Playoffs | 2018/09/29 21:00 | Prairie View A&M v Grambling State | W | 22-16 |
| NCAA Division I, FCS, Playoffs | 2018/09/22 23:00 | Prairie View A&M v Arkansas-Pine Bluff | W | 62-13 |
| NCAA Division I, FCS, Playoffs | 2018/09/16 02:00 | Prairie View A&M v UNLV | L | 17-46 |
| NCAA Division I, FCS, Playoffs | 2018/09/08 23:00 | Prairie View A&M v Sam Houston State | L | 32-41 |