Stadium: Shell Energy Stadium Round: 1
| NCAA Division I, FCS, Playoffs | 2019/10/19 19:00 | Southern v Texas Southern | W | 28-21 |
| NCAA Division I, FCS, Playoffs | 2018/10/20 19:00 | Texas Southern v Southern | W | 7-21 |
| NCAA Division I, FCS, Playoffs | 2017/11/11 23:00 | Texas Southern v Southern | W | 7-33 |
| NCAA Division I, FCS, Playoffs | 2021/03/06 19:30 | Arkansas-Pine Bluff v Southern | L | 33-30 |
| NCAA Division I, FCS, Playoffs | 2021/02/27 00:00 | Southern v Alabama State | W | 24-21 |
| NCAA Division I, FCS, Playoffs | 2019/12/07 21:00 | Southern v Alcorn State | L | 24-39 |
| NCAA Division I, FCS, Playoffs | 2019/11/30 22:00 | Southern v Grambling State | W | 30-28 |
| NCAA Division I, FCS, Playoffs | 2019/11/16 20:00 | Southern v Jackson State | W | 40-34 |
| NCAA Division I, FCS, Playoffs | 2019/11/09 22:00 | Southern v Virginia Lynchburg | W | 58-7 |
| NCAA Division I, FCS, Playoffs | 2019/11/02 21:00 | Alabama A&M v Southern | W | 31-35 |
| NCAA Division I, FCS, Playoffs | 2019/10/26 19:00 | Southern v Alcorn State | L | 13-27 |
| NCAA Division I, FCS, Playoffs | 2021/03/07 01:00 | Texas Southern v Prairie View A&M | L | 19-20 |
| NCAA Division I, FCS, Playoffs | 2019/11/23 21:00 | Texas Southern v Arkansas-Pine Bluff | L | 13-45 |
| NCAA Division I, FCS, Playoffs | 2019/11/09 20:00 | Alabama State v Texas Southern | L | 27-21 |
| NCAA Division I, FCS, Playoffs | 2019/11/02 19:00 | Texas Southern v Grambling State | L | 20-55 |
| NCAA Division I, FCS, Playoffs | 2019/10/26 19:00 | Texas Southern v Mississippi Valley | L | 14-35 |
| NCAA Division I, FCS, Playoffs | 2019/10/19 19:00 | Southern v Texas Southern | L | 28-21 |
| NCAA Division I, FCS, Playoffs | 2019/10/12 19:00 | Texas Southern v Missouri S&T | L | 20-23 |
| NCAA Division I, FCS, Playoffs | 2019/10/05 19:00 | Texas Southern v Alabama A&M | L | 28-35 |