Stadium: Strawberry Stadium Round: 1
Home Manager: Frank Scelfo Away Manager: David Bailiff
| NCAA Division I, FCS, Playoffs | 2022/09/24 23:00 | Texas A&M-Commerce v North American Stallions | W | 63-3 |
| NCAA Division I, FCS, Playoffs | 2022/09/17 23:00 | Texas A&M-Commerce v Sam Houston State | L | 17-27 |
| NCAA Division I, FCS, Playoffs | 2022/09/10 23:00 | Texas A&M-Commerce v Tennessee Tech | L | 25-26 |
| NCAA Division I, FCS, Playoffs | 2022/09/02 00:00 | Texas A&M-Commerce v Lincoln Oaklanders | W | 52-7 |
| NCAA Division I, FCS, Playoffs | 2021/11/13 22:00 | Texas A&M-Commerce v Eastern New Mexico | W | 30-10 |
| NCAA Division I, FCS, Playoffs | 2021/11/06 21:00 | Angelo State v Texas A&M-Commerce | L | 30-3 |
| NCAA Division I, FCS, Playoffs | 2021/10/30 21:00 | Texas A&M-Commerce v Texas-Permian Basin Falcons | W | 41-0 |
| NCAA Division I, FCS, Playoffs | 2021/10/23 23:00 | West Texas AM Buffaloes v Texas A&M-Commerce | W | 3-15 |
| NCAA Division I, FCS, Playoffs | 2022/10/01 23:00 | Murray State v SE Louisiana | W | 14-48 |
| NCAA Division I, FCS, Playoffs | 2022/09/24 23:00 | Incarnate Word v SE Louisiana | W | 35-41 |
| NCAA Division I, FCS, Playoffs | 2022/09/17 23:00 | Central Conn. State v SE Louisiana | W | 6-70 |
| NCAA Division I, FCS, Playoffs | 2022/09/10 22:00 | SE Louisiana v Florida Atlantic | L | 9-42 |
| NCAA Division I, FCS, Playoffs | 2022/09/03 23:00 | SE Louisiana v Lafayette | L | 7-24 |
| NCAA Division I, FCS, Playoffs | 2021/12/04 19:00 | SE Louisiana v James Madison | L | 20-59 |
| NCAA Division I, FCS, Playoffs | 2021/11/28 00:00 | Florida A&M v SE Louisiana | W | 14-38 |
| NCAA Division I, FCS, Playoffs | 2021/11/19 00:00 | Nicholls State v SE Louisiana | L | 45-42 |