Stadium: Hantz Stadium Round: 1
| NCAA Division I, FCS, Playoffs | 2022/10/29 20:00 | Tiffin Dragons v Northwood Timberwolves | L | 48-3 |
| NCAA Division I, FCS, Playoffs | 2022/10/22 18:00 | Lake Erie Storm v Northwood Timberwolves | L | 21-18 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 17:00 | Northwood Timberwolves v Hillsdale Chargers | L | 7-41 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 18:00 | Findlay Oilers v Northwood Timberwolves | L | 34-14 |
| NCAA Division I, FCS, Playoffs | 2022/10/01 23:00 | Ashland Eagles v Northwood Timberwolves | L | 56-17 |
| NCAA Division I, FCS, Playoffs | 2022/09/24 18:00 | Davenport Panthers v Northwood Timberwolves | L | 51-17 |
| NCAA Division I, FCS, Playoffs | 2022/09/17 17:00 | Northwood Timberwolves v Saginaw Valley State Cardinals | L | 14-35 |
| NCAA Division I, FCS, Playoffs | 2022/09/10 17:00 | Northwood Timberwolves v Madonna University Crusaders | W | 38-0 |
| NCAA Division I, FCS, Playoffs | 2022/10/22 17:00 | Ohio Dominican Panthers v Kentucky Wesleyan College Panthers | W | 49-7 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 23:00 | Ashland Eagles v Ohio Dominican Panthers | L | 14-7 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 16:00 | Lake Erie Storm v Ohio Dominican Panthers | W | 7-38 |
| NCAA Division I, FCS, Playoffs | 2022/10/01 17:00 | Ohio Dominican Panthers v Walsh | W | 21-0 |
| NCAA Division I, FCS, Playoffs | 2022/09/24 17:00 | Ohio Dominican Panthers v Indianapolis Greyhounds | L | 38-44 |
| NCAA Division I, FCS, Playoffs | 2022/09/17 17:00 | Ohio Dominican Panthers v William Jewell | W | 31-21 |
| NCAA Division I, FCS, Playoffs | 2022/09/10 17:00 | Tiffin Dragons v Ohio Dominican Panthers | L | 28-13 |
| NCAA Division I, FCS, Playoffs | 2022/09/03 16:00 | Ohio Dominican Panthers v Findlay Oilers | W | 28-14 |